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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF1C All Species: 43.94
Human Site: Y341 Identified Species: 69.05
UniProt: O43896 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43896 NP_006603.2 1103 122947 Y341 E T L S T L R Y A D R T K Q I
Chimpanzee Pan troglodytes XP_511296 1097 122335 Y341 E T L S T L R Y A D R T K Q I
Rhesus Macaque Macaca mulatta XP_001117788 1214 134234 Y452 E T L S T L R Y A D R T K Q I
Dog Lupus familis XP_546571 1191 131317 Y428 E T L S T L R Y A D R T K Q I
Cat Felis silvestris
Mouse Mus musculus O35071 1100 122416 Y341 E T L S T L R Y A D R T K Q I
Rat Rattus norvegicus O35787 1097 122315 Y340 E T L S T L R Y A D R T K Q I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509769 1770 199343 Y341 E T L S T L R Y A D R A K Q I
Chicken Gallus gallus XP_417608 1757 197902 Y341 E T L S T L R Y A D R A K Q I
Frog Xenopus laevis Q91784 1226 138905 E391 E N L Q S L M E R N K N L E K
Zebra Danio Brachydanio rerio XP_699380 1180 133432 Y342 E T L S T L R Y A D R A K Q I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZAJ2 1670 189326 Y344 E T L S T L R Y A D R A K Q I
Honey Bee Apis mellifera XP_397276 1682 191012 Y342 E T L S T L R Y A D R A K Q I
Nematode Worm Caenorhab. elegans P23678 1584 179603 L338 F D E T L S T L R Y A D R A K
Sea Urchin Strong. purpuratus P46872 699 78679 F94 E G Y N G T I F A Y G Q T G T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 F323 E T L S T L R F G M R A K S I
Conservation
Percent
Protein Identity: 100 99 89.6 87.7 N.A. 94.1 92.7 N.A. 38.1 38.7 23.9 60.4 N.A. 30.7 36.2 30.3 27.6
Protein Similarity: 100 99 89.9 89.3 N.A. 95.5 94.6 N.A. 48.6 48.4 42.3 71.8 N.A. 42.8 47.6 43.5 41
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 93.3 93.3 20 93.3 N.A. 93.3 93.3 0 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 93.3 46.6 93.3 N.A. 93.3 93.3 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 26.5
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 43.7
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 66.6
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 80 0 7 40 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 0 0 0 0 0 74 0 7 0 0 0 % D
% Glu: 94 0 7 0 0 0 0 7 0 0 0 0 0 7 0 % E
% Phe: 7 0 0 0 0 0 0 14 0 0 0 0 0 0 0 % F
% Gly: 0 7 0 0 7 0 0 0 7 0 7 0 0 7 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 80 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 7 0 80 0 14 % K
% Leu: 0 0 87 0 7 87 0 7 0 0 0 0 7 0 0 % L
% Met: 0 0 0 0 0 0 7 0 0 7 0 0 0 0 0 % M
% Asn: 0 7 0 7 0 0 0 0 0 7 0 7 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 7 0 0 0 0 0 0 0 7 0 74 0 % Q
% Arg: 0 0 0 0 0 0 80 0 14 0 80 0 7 0 0 % R
% Ser: 0 0 0 80 7 7 0 0 0 0 0 0 0 7 0 % S
% Thr: 0 80 0 7 80 7 7 0 0 0 0 40 7 0 7 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 0 74 0 14 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _